Coenzyme Q10

The Best Coenzyme Q10 Supplements

Until a few years ago, there were only inactive coenzyme Q10 supplements (ubiquinone or ubiquinone). Fortunately for those over 40, there is now active Q10 in the form of Ubiquinol.

Disadvantages Q10

The older we get, the more difficult it is for our bodies to convert ubiquinone (Q10) into the active ubiquinol. And if that conversion does not take place, it is of no use to us.

This is why it is very important for people aged 40 and older to choose Ubiquinol. The highest quality comes from Kaneka.

People who buy Coenzyme Q10 also use:

• Vitamin K2
• Fish oil
• Vitamin D3
• PQQ
• Vitamin C
• Red Yeast Rice

Discovery of Coenzyme Q10

Coenzyme Q10 was discovered in 1957 by Professor Fred Crane who isolated it from mitochondria of a bovine heart and was able to demonstrate that it is essential for ATP production. Until Kaneka was able to make natural coenzyme Q10 in its oxidized form via a yeast fermentation process in the 1970s, it was only available as an extraction product from bovine heart. Coenzyme Q10 became better known early this century after several governments allowed its use in higher doses and based on Kaneka's extensive safety studies.

Statins, Red Yeast Rice and Q10

Statins work by lowering the bodily production of cholesterol, but have the side effect of decreasing the level of Ubiquinol in the body.

The most common side effect of statins is myalgia (muscle pain). Studies have shown that this side effect is much more common in people who have low levels of Ubiquinol in the body.

That is why it is very important to take a Q10 or Ubiquinol supplement when taking Statins (or Red Yeast Rice).

How much Q10 equals Ubiquinol?

Only the Best Coenzyme Q10 - from Kaneka

Kaneka products contain Kaneka Corporation's 100% natural coenzyme Q10. This is the highest quality Ubiquinol available. Almost all clinical studies have been done with Kaneka ingredients.

Nature-Identical and Good Absorption

Since 1977, Kaneka has been the only manufacturer of yeast-fermented natural CoQ10. This form is bio-identical to CoQ10 in the body. Kaneka now has over 30 years of experience in manufacturing, safety and clinical studies that has ensured unprecedented quality.

Kaneka is an originally Japanese manufacturer of "ingredients" based on innovation. Kaneka's products are used in various industries such as construction, packaging, automotive, but also the pharmaceutical industry. Kaneka has plants on all continents and was the first Japanese chemical company to become active in Europe (opening a plant in Oevel in the 1970s).

In addition to this production plant, Kaneka in Belgium also has a majority stake in Eurogentec (Liège), which is a major player in the production of vaccines. Kaneka makes nutrients under c-GMP, has specifications that are stricter than those of various pharmacopoeias, complies with various ISO standards and has special attention to the environment.

Coenzyme Q10 was discovered in 1957 by Professor Fred Crane who isolated it from mitochondria of a bovine heart and was able to demonstrate that it is essential for ATP production. Until Kaneka was able to make natural coenzyme Q10 in its oxidized form via a yeast fermentation process in the 1970s, it was only available as an extraction product from bovine heart. Coenzyme Q10 became better known early this century after several governments allowed its use in higher doses and based on Kaneka's extensive safety studies.

Is all Q10 derived from Kaneka?

In addition to Kaneka Q10, which is the purest oxidized Q10, a number of manufacturers have introduced a less pure and even synthetic form. Q10, besides Kaneka, which makes pharmaceutical grade (we still have ongoing drug registrations) is currently only made by Chinese companies. To be sure that a product contains Kaneka Q10, it is important to look for a mention to Kaneka on the packaging. If you do not see such a mention, then it is most likely Chinese Q10.

What is the difference between coenzyme Q10 and Ubiquinol?

There are two forms in which CoQ10 occurs: ubiquinol (the active form) and ubiquinone (the oxidized form). Ubiquinol is the form in which CoQ10 occurs naturally in the body. In blood plasma in a young and healthy body, more than 95% of all CoQ10 occurs in the ubiquinol form.

So, in simple terms: the biologically active form. This active form does not need to be converted. Therefore, it is better and more easily absorbed by the body and also works faster.

How do you ensure that the body gets enough, and is this possible through diet?

There are several foods that contain ubiquinol, but we would have to eat huge amounts of them to get enough: for example, 3 kg of red meat or 60 avocados a day. Therefore, a dietary supplement in the form of Ubiquinol is the way to go.

Who is it recommended for?

Young individuals in good health who eat a healthy diet already make enough themselves or can convert coenzyme Q10 into Ubiquinol. But as we age, natural production decreases dramatically. For example, when we are 40 we already have 30 percent less in the heart muscle than when we are 20.

Besides age, there are other factors that can cause deficiencies: increased demand by the body (e.g., when exercising), increased stress, insufficient intake of it (or of its building blocks) through diet, gene mutation, use of certain medications (e.g., statins or cholesterol drugs).

Athletes consume more Ubiquinol when they exercise and they need a supplemental dose of this essential substance daily. Therefore, supplementation is strongly recommended in the aforementioned cases.

What dosage should I choose?

The recommended dosage varies from individual to individual. However, the elderly or people who suspect that their ubiquinol levels have dropped can start with an intake of 200 mg per day. Usually the dose is halved after four weeks.

Studies have shown that most people who take 100 mg a day for one week feel a marked difference. Clinicians assume that a standard recommended dose to build healthy ubiquinol levels is 50 to 200 mg per day.

It is a perfectly safe substance and you cannot take too much of it. Ubiquinol is usually taken with breakfast but it can also be taken with dinner.

Updated December 10, 2023